$165 million investment fund established for 51 SW Iowa communities

Iowa Senator Chuck Grassley says President Trump’s signature on a bill that classifies fentanyl-related drugs as more dangerous substances “will save

A south central Iowa man is in custody after a fatal shooting in Appanoose County. Appanoose County Sheriff Gary Anderson says

Virginia’s governor will headline an Iowa GOP fundraiser tonight, another in a growing list of potential 2028 presidential candidates making trips

More than one in every ten Iowans is diabetic, and studies show more than 19,000 Iowans are being diagnosed with diabetes

Visitors to Iowa’s largest zoo may have to be patient, but they should now be able to spot the newest resident,

Next week’s RAGBRAI — the Register’s Annual Great Bicycle Ride Across Iowa — will cross into a neighboring state for the

The U.S. Senate is debating a package of $9 billion in federal budget cuts, carrying out many of the cuts identified

Racing and Gaming Administrator Tina Eick  says the money bet on sports went up in Iowa in the fiscal year that

A business professor at the University of Iowa says she’s stunned by the results of a new survey that finds some